CKB项目在践行科学数据开放共享的同时，也主动与国内不同领域的顶尖科研团队联手，充分利用各方资源优势和人才优势，协同攻关，在某些科学问题上实现突破，取得了一系列重要的研究成果。截至目前发表研究成果35篇，其中英文33篇，中文2篇。

例如，与南京医科大学沈洪兵院士团队合作，发现对遗传高危人群进行生活方式干预，胃癌的一级预防效果更好；利用遗传风险指标可优化肺癌筛查策略，提高二级预防效果。

与华中科技大学邬堂春院士团队合作，揭示了家用固体燃料产生的室内空气污染是居民过早死亡的重要原因之一，提出改用清洁能源和有效通风的预防措施。

与复旦大学阚海东教授团队合作，揭示了长期PM2.5暴露增加心血管病风险，可能抵消甚至逆转户外体力活动的心血管保护作用；另外，高PM2.5暴露与食管癌风险增加相关。

与中国医学科学院王辰院士团队合作，全面评价吸烟的健康危害，确定吸烟可显著增加56种疾病的发生风险。

与北京协和医院杜斌教授团队合作，揭示了低体重、正常体重偏低和向心性肥胖是脓毒血症相关死亡的重要危险因素。

与中国疾控中心赵丽云研究员团队合作，明确了普及健康生活方式可提高中国人群30岁时的期望寿命。

跨机构、跨领域优秀科研团队的合作可以促进科技创新资源的互补共享，更好地整合优化科技资源和要素，形成强大的创新源。未来，项目将继续积极推动基于脱敏数据的广泛合作，与国内外优秀科研团队一起研究中国的科学数据、解决中国的科学问题，充分发挥我国人群队列资源优势，构筑全球医学科技创新高地。

联合发表研究成果清单：

1. Liu N, Pan XF, Yu C, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Wu T, Chen Z, Pan A, Li L; China Kadoorie Biobank Collaborative Group. Association of Major Depression With Risk of Ischemic Heart Disease in a Mega-Cohort of Chinese Adults: The China Kadoorie Biobank Study. J Am Heart Assoc. 2016; 5(12):e004687.

2. Sun J, Ma H, Yu C, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Shen H, Chen Z, Hu Z, Li L; China Kadoorie Biobank Collaborative Group. Association of Major Depressive Episodes With Stroke Risk in a Prospective Study of 0.5 Million Chinese Adults. Stroke. 2016;47(9):2203-8.

3. Pan R, Zhu M, Yu C, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Hu Z, Chen Z, Li L, Shen H; China Kadoorie Biobank Collaborative Group. Cancer incidence and mortality: A cohort study in China, 2008-2013. Int J Cancer. 2017;141(7):1315-1323.

4. Dong W, Pan XF, Yu C, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Wu T, Chen Z, Pan A, Li L; China Kadoorie Biobank Collaborative Group. Self-Rated Health Status and Risk of Ischemic Heart Disease in the China Kadoorie Biobank Study: A Population-Based Cohort Study. J Am Heart Assoc. 2017;6(9):e006595.

5. Tian T, Jin G, Yu C, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Shen H, Chen Z, Hu Z, Li L; China Kadoorie Biobank Collaborative Group. Family History and Stroke Risk in China: Evidence from a Large Cohort Study. J Stroke. 2017;19(2):188-195.

6. Pan XF, He M, Yu C, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Wu T, Chen Z, Pan A, Li L; China Kadoorie Biobank Collaborative Group. Type 2 Diabetes and Risk of Incident Cancer in China: A Prospective Study Among 0.5 Million Chinese Adults. Am J Epidemiol. 2018;187(7):1380-1391.

7. Song X, Wu J, Yu C, Dong W, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Chen Z, Pan A, Li L; China Kadoorie Biobank Collaborative Group. Association between multiple comorbidities and self-rated health status in middle-aged and elderly Chinese: the China Kadoorie Biobank study. BMC Public Health. 2018; 18(1):744.

8. Meng R, Liu N, Yu C, Pan X, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Chen Z, Pan A, Li L; China Kadoorie Biobank collaborative group. Association between major depressive episode and risk of type 2 diabetes: A large prospective cohort study in Chinese adults. J Affect Disord. 2018; 234:59-66.

9. Dong W, Pan XF, Yu C, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Wu T, Chen Z, Pan A, Li L; China Kadoorie Biobank Collaborative Group. Self-Rated Health Status and Risk of Incident Stroke in 0.5 Million Chinese Adults: The China Kadoorie Biobank Study. J Stroke. 2018;20(2):247-257.

10. Yu K, Qiu G, Chan KH, Lam KH, Kurmi OP, Bennett DA, Yu C, Pan A, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Hu FB, Chen Z, Li L, Wu T. Association of Solid Fuel Use With Risk of Cardiovascular and All-Cause Mortality in Rural China. JAMA. 2018;319(13):1351-1361.

11. Song C, Lv J, Liu Y, Chen JG, Ge Z, Zhu J, Dai J, Du LB, Yu C, Guo Y, Bian Z, Yang L, Chen Y, Chen Z, Liu J, Jiang J, Zhu L, Zhai X, Jiang Y, Ma H, Jin G, Shen H, Li L, Hu Z; China Kadoorie Biobank Collaborative Group. Associations Between Hepatitis B Virus Infection and Risk of All Cancer Types. JAMA Netw Open. 2019;2(6): e195718.

12. Dai J, Lv J, Zhu M, Wang Y, Qin N, Ma H, He YQ, Zhang R, Tan W, Fan J, Wang T, Zheng H, Sun Q, Wang L, Huang M, Ge Z, Yu C, Guo Y, Wang TM, Wang J, Xu L, Wu W, Chen L, Bian Z, Walters R, Millwood IY, Li XZ, Wang X, Hung RJ, Christiani DC, Chen H, Wang M, Wang C, Jiang Y, Chen K, Chen Z, Jin G, Wu T, Lin D, Hu Z, Amos CI, Wu C, Wei Q, Jia WH, Li L, Shen H. Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. Lancet Respir Med. 2019;7(10):881-891.

13. 朱猛,吕筠,余灿清,靳光付,郭彧,卞铮,Robin Walters, Iona Millwood,陈铮鸣,沈洪兵,胡志斌,李立明.中国不同地区群体遗传结构差异及调整策略研究[J].中华流行病学杂志,2019,40(1):20-25.

14. Tian T, Lv J, Jin G, Yu C, Guo Y, Bian Z, Yang L, Chen Y, Shen H, Chen Z, Hu Z, Li L; China Kadoorie Biobank Collaborative Group. Tea consumption and risk of stroke in Chinese adults: a prospective cohort study of 0.5 million men and women. Am J Clin Nutr. 2020;111(1):197-206.

15. Weng L, Fan J, Yu C, Guo Y, Bian Z, Wei Y, Yang L, Chen Y, Du H, Chang L, Gong W, Chen J, Chen Z, Du B, Lv J, Li L. Body-mass index and long-term risk of sepsis-related mortality: a population-based cohort study of 0.5 million Chinese adults. Crit Care. 2020;24(1):534.

16. Wang L, Jin G, Yu C, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Hu Z, Chen F, Chen Z, Li L, Shen H; China Kadoorie Biobank Collaborative Group. Cancer incidence in relation to body fatness among 0.5 million men and women: Findings from the China Kadoorie Biobank. Int J Cancer. 2020;146(4):987-998.

17. Meng R, Yu C, Liu N, He M, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Zhang X, Chen Z, Wu T, Pan A, Li L; China Kadoorie Biobank Collaborative Group. Association of Depression With All-Cause and Cardiovascular Disease Mortality Among Adults in China. JAMA Netw Open. 2020;3(2):e1921043.

18. Yu K, Lv J, Qiu G, Yu C, Guo Y, Bian Z, Yang L, Chen Y, Wang C, Pan A, Liang L, Hu FB, Chen Z, Li L, Wu T; China Kadoorie Biobank Study. Cooking fuels and risk of all-cause and cardiopulmonary mortality in urban China: a prospective cohort study. Lancet Glob Health. 2020;8(3): e430-e439.

19. Jin G, Lv J, Yang M, Wang M, Zhu M, Wang T, Yan C, Yu C, Ding Y, Li G, Ren C, Ni J, Zhang R, Guo Y, Bian Z, Zheng Y, Zhang N, Jiang Y, Chen J, Wang Y, Xu D, Zheng H, Yang L, Chen Y, Walters R, Millwood IY, Dai J, Ma H, Chen K, Chen Z, Hu Z, Wei Q, Shen H, Li L. Genetic risk, incident gastric cancer, and healthy lifestyle: a meta-analysis of genome-wide association studies and prospective cohort study. Lancet Oncol. 2020;21(10):1378-1386.

20. Qiu G, Yu K, Yu C, Li W, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Chen Z, Hu FB, Li L, Wu T. Association of exhaled carbon monoxide with risk of cardio-cerebral-vascular disease in the China Kadoorie Biobank cohort study. Sci Rep. 2020;10(1):19507.

21. Song C, Lv J, Yu C, Zhu M, Yu C, Guo Y, Yang L, Chen Y, Chen Z, Jiang T, Ma H, Jin G, Shen H, Hu Z, Li L. Adherence to Healthy Lifestyle and Liver cancer in Chinese: a prospective cohort study of 0.5 million people. Br J Cancer. 2022 ;126(5):815-821.

22. Yu C, Song C, Lv J, Zhu M, Yu C, Guo Y, Yang L, Chen Y, Chen Z, Jiang T, Ma H, Jin G, Shen H, Hu Z, Li L; China Kadoorie Biobank Collaborative Group. Prediction and clinical utility of a liver cancer risk model in Chinese adults: A prospective cohort study of 0.5 million people. Int J Cancer. 2021 ;148(12):2924-2934.

23. Zheng J, Zhang Y, Rasheed H, Walker V, Sugawara Y, Li J, Leng Y, Elsworth B, Wootton RE, Fang S, Yang Q, Burgess S, Haycock PC, Borges MC, Cho Y, Carnegie R, Howell A, Robinson J, Thomas LF, Brumpton BM, Hveem K, Hallan S, Franceschini N, Morris AP, Köttgen A, Pattaro C, Wuttke M, Yamamoto M, Kashihara N, Akiyama M, Kanai M, Matsuda K, Kamatani Y, Okada Y, Walters R, Millwood IY, Chen Z, Davey Smith G, Barbour S, Yu C, Åsvold BO, Zhang H, Gaunt TR. Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease. Int J Epidemiol. 2022;50(6):1995-2010.

24. Weng L, Hu Y, Sun Z, Yu C, Guo Y, Pei P, Yang L, Chen Y, Du H, Pang Y, Lu Y, Chen J, Chen Z, Du B, Lv J, Li L. Place of death and phenomenon of going home to die in Chinese adults: A prospective cohort study. Lancet Reg Health West Pac. 2021;18: 100301.

25. 朱猛,吕筠,余灿清,黄艳倩,马红霞,靳光付,郭彧,裴培,陈铮鸣,沈洪兵,胡志斌*,李立明*.多基因遗传风险评分指导肺癌个体化筛查的前瞻性队列研究[J].中华流行病学杂志,2021,42(3):376-381.

26. Sun Q, Yu D, Fan J, Yu C, Guo Y, Pei P, Yang L, Chen Y, Du H, Yang X, Sansome S, Wang Y, Zhao W, Chen J, Chen Z, Zhao L, Lv J, Li L; China Kadoorie Biobank Collaborative Group. Healthy lifestyle and life expectancy at age 30 years in the Chinese population: an observational study. Lancet Public Health. 2022;7(12):e994-e1004.

27. Chan KH#, Wright N#, Xiao D, Guo Y, Chen Y, Du H, Yang L, Millwood IY, Pei P, Wang J, Turnbull I, Gilbert S, Avery D, Kartsonaki C, Yu C, Chen J, Lv J, Clarke R, Collins R, Peto R, Li L*, Wang C*, Chen Z*. Tobacco smoking and risks of more than 470 diseases in China: a prospective cohort study. Lancet Public Health. 2022;7(12):e1014-e1026.

28. Liu C#, Chan KH#, Lv J#, Lam H, Newell K, Meng X, Liu Y, Chen R, Kartsonaki C, Wright N, Du H, Yang L, Chen Y, Guo Y, Pei P, Yu C, Shen H, Wu T, Kan H*, Chen Z*, Li L*. Long-Term Exposure to Ambient Fine Particulate Matter and Incidence of Major Cardiovascular Diseases: A Prospective Study of 0.5 Million Adults in China. Environ Sci Technol. 2022;56(18):13200-13211.

29. Yu K, Lv J, Liu G, Yu C, Guo Y, Yang L, Chen Y, Wang C, Chen Z, Li L, Wu T. Cooking and future risk of all-cause and cardiopulmonary mortality. Nat Hum Behav. 2023;7(2):200-210.

30. Zhu X, Lv J, Zhu M, Yan C, Deng B, Yu C, Guo Y, Ni J, She Q, Wang T, Wang J, Jiang Y, Chen J, Hang D, Song C, Gao X, Wu J, Dai J, Ma H, Yang L, Chen Y, Song M, Wei Q, Chen Z, Hu Z, Shen H, Ding Y, Li L, Jin G. Development, validation, and evaluation of a risk assessment tool for personalized screening of gastric cancer in Chinese populations. BMC Med. 2023;21(1):159.

31. Zhang Y, Yu C, Chen S, Tu Z, Zheng M, Lv J, Wang G, Liu Y, Yu J, Guo Y, Yang L, Chen Y, Guo K, Yang K, Yang H, Zhou Y, Jiang Y, Zhang X, He M, Liu G, Chen Z, Wu T, Wu S, Li L, Pan A. Ideal cardiovascular health and mortality: pooled results of three prospective cohorts in Chinese adults. Chin Med J (Engl). 2023;136(2):141-149.

32. Sun D, Liu C, Zhu Y, Yu C, Guo Y, Sun D, Pang Y, Pei P, Du H, Yang L, Chen Y, Meng X, Liu Y, Zhang J, Schmidt D, Avery D, Chen J, Chen Z, Lv J, Kan H, Li L; China Kadoorie Biobank Collaborative Group. Long-Term Exposure to Fine Particulate Matter and Incidence of Esophageal Cancer: A Prospective Study of 0.5 Million Chinese Adults. Gastroenterology. 2023;165(1):61-70.

33. Sun D, Liu C, Ding Y, Yu C, Guo Y, Sun D, Pang Y, Pei P, Du H, Yang L, Chen Y, Meng X, Liu Y, Liu J, Sohoni R, Sansome G, Chen J, Chen Z, Lv J, Kan H, Li L; China Kadoorie Biobank Collaborative Group. Long-term exposure to ambient PM2·5, active commuting, and farming activity and cardiovascular disease risk in adults in China: a prospective cohort study. Lancet Planet Health. 2023;7(4):e304-e312.

34. Ma Z, Lv J, Zhu M, Yu C, Ma H, Jin G, Guo Y, Bian Z, Yang L, Chen Y, Chen Z, Hu Z, Li L, Shen H. Lung cancer risk score for ever and never smokers in China. Cancer Commun (Lond). 2023;43(8):877-895.

35. Ji C, Lv J, Zhang J, Zhu M, Yu C, Ma H, Jin G, Guo Y, Pei P, Yang L, Chen Y, Du H, Chen Z, Hu Z, Li L, Shen H; China Kadoorie Biobank Collaborative Group. Household air pollution and risk of incident lung cancer in urban China: A prospective cohort study. Int J Cancer. 2023; doi: 10.1002/ijc.34646.